Methandrostenolone

10mg/ tab, 100tabs

Description

Methandrostenolone binds to and activates the androgen receptor (AR) in order to exert its effects. These include dramatic increases in protein synthesis, glycogenolysis, and muscle strength over a short space of time.

Pharmacokinetics

Methandrostenolone has high oral bioavailability. It has very low affinity for human serum sex hormone-binding globulin (SHBG), about 10% of that of testosterone and 2% of that of DHT. The drug is metabolized in the liver. Methandrostenolone does not produce 5α-reduced metabolites. The elimination half-life of Methandrostenolone is about 3 to 6 hours. It is eliminated in the urine.

Indications and Usage

Males: Methandrostenolone increases muscular mass, hardness and strength without water retention, low estrogenic activity

Females: Methandrostenolone may be used in postmenopausal women with advancing inoperable breast cancer.

Contradictions

Hypersensitivity to the substance or excipients.

Methandrostenolone is contradicted in men with the breast carcinomas or with known or suspected prostate carcinomas or liver/renal diseases

Dosage and administration

Methandrostenolone propionate is for intramuscular injections only. Males: 10-50 mg per day.

Warnings

Methandrostenolone, through its metabolic effects, stimulates the nervous, mental, and physical activities of a patient. Therefore, it should be used with caution in the presence of cardiovascular and renal diseases, especially in elderly males. Prolonged administration or excessive dosage may cause inhibition of testicular function( oligospermia and/or decrease of ejaculation volume). Women should be observed for signs of virilization. Discontinuation of drug therapy at the mild virilism is necessary to prevent irreversible virilization. Anaphylactic reactions, although rare, may occur, and treatment should be readily available. Hypersensitivity reactions, including rash and dermatitis, have been reported.

Drug interactions

Anabolic steroids may increase sensitivity to oral anticoagulants. Dosage of the anticoagulant may have to be adjusted in order to maintain the prothrombin time at the desired therapeutic level. Patients receiving oral anticoagulant therapy require close monitoring, especially when starting or stopping taking anabolic steroids.

Adverse effects

The side effects include bloating or water retention and gynecomastia. It has a significant androgenic side-effects that one should expect when using this steroid. This may include bouts of oily skin, acne, and body/facial hair growth. Anabolic/androgenic steroids may also aggravate male pattern hair loss. Anabolic/androgenic steroids can have deleterious effects on serum cholesterol. This includes a tendency to reduce HDL (good) cholesterol values and increase LDL (bad) cholesterol values, which may shift the HDL to LDL balance in a direction that causes greater risk of arteriosclerosis. It could shut down the production of testosterone, so users should be careful to use it in post cycle therapy because it can interfere with recovery.

Overdose

There have been no reports of acute overdosing with this substance. Symptomatic treatment should be provided.

Storage

Store in a dark, dry place. Keep away from children.

Presentation

Tablet in vial, or pvc-alu blisters